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Many women who are living with obesity or have polycystic ovary syndrome will have irregular menstrual cycles and ovulation, which makes it difficult for them to get pregnant, said Daniel Drucker, senior scientist at Sinai Healths Lunenfeld-Tanenbaum Research Institute in Toronto

In cases of inoperability, radiotherapy, imiquimod, 5-flourouracil, photodynamic and target treatment for the hedgehog pathway can be other options for treatment (37)